[1]曹思明,韩立杰,张玲,等.榛花粉不同提取物组分抗癌症活性研究[J].延边大学学报(自然科学版),2016,42(01):45-47.
　CAO Siming,HAN Lijie,ZHANG Ling,et al.Research on anticancer activity of different extracts in hazel pollen[J].Journal of Yanbian University,2016,42(01):45-47.
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榛花粉不同提取物组分抗癌症活性研究

《延边大学学报(自然科学版)》[ISSN:1004-4353/CN:22-1191/N] 卷: 第42卷 期数: 2016年01期 页码: 45-47 栏目: 基础科学研究 出版日期: 2016-03-20
Title:
Research on anticancer activity of different extracts in hazel pollen
作者:
曹思明1;  韩立杰2;  张玲2;  金铁岩1; 2*
1.延边大学理学院 化学系, 吉林 延吉 133002; 2.延边大学农学院 食品科学系, 吉林 延吉 133002
Author(s):
CAO Siming1;  HAN Lijie2;  ZHANG Ling2;  JIN Tieyan1; 2*
1.Department of Chemistry, College of Science, Yanbian University, Yanji 133002, China; 2.Department of Food Science, College of Agriculture, Yanbian University, Yanji 133002, China
关键词:
榛花粉;  榛花粉提取物;  抗癌活性
Keywords:
hazel pollen;  hazel pollen extract;  anticancer activity
分类号:
TS202.1
文献标志码:
A
摘要:
以榛花粉为原材料,首先利用乙醇浸泡榛花粉得到乙醇提取物,然后分别利用不同溶剂对榛花粉乙醇提取物进行萃取得到不同组分,利用MTT比色法测量榛花粉各提取组分对胃癌细胞(AGS)和肝癌细胞(SK-Hep1)生长的体外抑制作用.实验结果表明:榛花粉各提取组分对胃癌细胞均具有很好的抑制作用,对肝癌细胞的抑制活性较低,其中二氯甲烷组分对癌症细胞的抑制活性均高于其他各组分.
Abstract:
Hazel pollen acted as raw material, and ethanol was used as extraction solvent to obtain the hazel pollen extracts. The extracts was tested with MTT assay after further extracted with different solvent to understand their effect on growth inhibition of in vitro test of human gastric carcinoma cells(AGS)and human liver adenocarcinoma cells(SK-Hep1). The results show that hazel pollen extract components have a good inhibition of gastric cancer but lower inhibitory activity in liver cancer; Dichloromethane extractes show higher inhibitory activity of cancer cells than the others.

参考文献/References:

[1] 刘峰,魏新庭,王冬冬.抗癌药物的研究现状[J].聊城大学学报(自然科学版),2006,19(1):39-43.
[2] 聂纯.天然药物抗癌有效成分研究进展[J].中草药,1999,30(1):65-69.
[3] 唐春风,梁洁,彭玉德.天然抗癌药物研究进展[J].广西医学,2006,28(6):946-948.
[4] 萧伟,陈凤龙,章成峰,等.国内外天然药物的发展现状和趋势[J].中草药,2009,11(11):1681-1687.
[5] 白玉华,孙颖,于春月,等.榛花挥发油的化学成分[J].药学与临床研究,2010,18(3):265-266.
[6] 栾芳,赵艳丽,李锦莲,等.榛花中八种金属元素分析鉴别[J].黑龙江医药科学,2014,37(5):31-32.
[7] 蔡英茂.榛花对糖尿病小鼠肝组织糖原合成的影响[J].中国中医药科技,2008,15(4):322.
[8] 郭芳彬.花粉的抗癌作用机理浅析[J].蜜蜂杂志,2006,26(6):38-40.
[9] 周康,杨芳,姚娜,等.花粉的营养及功能概述[J].农产品加工(学刊),2013(10):60-63.
[10] 于淑玲,杜丽敏.花粉的营养价值和综合利用[J].中国食物与营养,2007(1):43-44.
[11] Stockerta J C, Blázquez-Castroa A, Canetea M, et al. MTT assay for cell viability: intracellular localization of the formazan product is in lipid droplets[J]. Acta Histochemica, 2012,114(8):785-796.
[12] 马金霞,潘世扬,张卫,等.MTT比色法用于肿瘤细胞体外药物敏感性试验的检测[J].临床检验杂志,2002,20(2):104.
[13] 林秋生.菱壳生物活性成分分析及抗胃癌机制研究[D].杭州:浙江大学,2013.

相似文献/References:

[1]曹思明,韩立杰,张玲,等.榛花粉不同提取物组分抗炎症活性研究[J].延边大学学报(自然科学版),2015,41(04):326.
　CAO Siming,HAN Lijie,ZHANG Ling,et al.Research of anti-inflammatory activity for difference Hazel pollen extracts[J].Journal of Yanbian University,2015,41(01):326.

备注/Memo

收稿日期: 2015-12-23 *通信作者: 金铁岩(1968—),男,博士,副教授,研究方向为功能性食品.

更新日期/Last Update: 2016-01-20