|本期目录/Table of Contents|

[1]衣涛,金英今,贾静杰,等.北豆根化学成分及其活性研究[J].延边大学学报(自然科学版),2017,(02):128-130.
 YI Tao,JIN Yingjin,JIA Jingjie,et al.Study on chemical constituents from rhizome of menispermum dauricum[J].Journal of Yanbian University,2017,(02):128-130.
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北豆根化学成分及其活性研究()
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《延边大学学报(自然科学版)》[ISSN:1004-4353/CN:22-1191/N]

卷:
期数:
2017年02期
页码:
128-130
栏目:
基础科学研究
出版日期:
2017-07-20

文章信息/Info

Title:
Study on chemical constituents from rhizome of menispermum dauricum
作者:
衣涛1 金英今2 贾静杰2 李熙峰2*
1.吉林烟草工业有限责任公司, 吉林 延吉 133000; 2.延边大学理学院 化学系, 吉林 延吉 133002
Author(s):
YI Tao1 JIN Yingjin2 JIA Jingjie2 LI Xifeng2*
1.Jilin Tobacco Industry Co., Ltd., Yanji 133000, China; 2.Department of Chemistry, College of Science, Yanbian University, Yanji 133002, China
关键词:
北豆根 自由基清除活性 蝙蝠葛啡碱 蝙蝠葛宁碱
Keywords:
menispermum dauricum free radical scavenging activity menisporphine dauriporphine
分类号:
R284..1
DOI:
-
文献标志码:
A
摘要:
利用超声辅助溶剂提取法,正、反相柱色谱及半制备HPLC等分离纯化手段,从植物北豆根中分离得到2个化合物,并利用核磁共振、质谱、红外光谱等对其进行结构鉴定,结果显示这2个化合物分别为蝙蝠葛啡碱(menisporphine)和蝙蝠葛宁碱(dauriporphine).活性实验结果表明,这2个化合物均具有较好的自由基清除活性,抑制率分别为99.8%和92.4%.本文实验结果可为抗氧化和抗老化药物的开发研究提供实验依据.
Abstract:
Two compounds were separated and purified from menispermum dauricum using ultrasonic-assisted solvent extraction technology, normal or reverse phase column chromatography and semi-preparative HPLC etc. Their structures were established by NMR, MS and IR spectroscopy experiments. The two compounds were determined as menisporphine(1)and dauriporphine(2). Compounds 1 and 2 showed remarkable scavenging activity toward DPPH. Inhibition rate are 99.8% and 92.4%, respectively. The results of this paper provide experimental basis for the development of anti-oxidation and anti-aging drugs.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期: 2017-05-24 基金项目: 吉林省科技发展计划项目(20140101044JC)
*通信作者: 李熙峰(1969—),男,教授,研究方向为天然物化学.
更新日期/Last Update: 2017-06-20